Creating new antibiotics using peptide nucleic acids
Official title: Development of peptide nucleic acid antibiotics-supplement 1
Funded at Nubad, LLC · NIH-10835557 · Data updated 2026-11-12
This study is working on creating new antibiotics that can better fight stubborn bacterial infections, especially for patients who have limited treatment options, by using special molecules to target the bacteria more effectively.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nubad, LLC NIH-funded |
| Lab location | 1 site (Greer, United States) |
| Project start | February 10, 2021 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $133,089 |
| NIH project number | 3R42AI114114-05S1 |
| Project ID | NIH-10835557 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would be individuals suffering from bacterial infections that are resistant to current antibiotic treatments.
✕Less likely to help
Patients with viral infections or those who do not have antibiotic-resistant bacterial infections may not receive any benefit from this research.
What this research studies
This research focuses on developing innovative antibiotics that target bacterial infections by utilizing peptide nucleic acids. The project involves training a candidate in organic chemistry to explore novel chemical methods and biophysical techniques for synthesizing and testing these new antibacterial agents. By identifying compounds that bind to ribosomal RNA, the research aims to enhance the effectiveness of antibiotic therapies against resistant bacteria. Patients may benefit from new treatment options that are more effective against infections that currently have limited treatment alternatives.
Why it matters
Potential benefit: If successful, this research could lead to the development of new antibiotics that effectively combat antibiotic-resistant infections.
How similar studies have gone: Other research has shown promise in developing novel antibiotics using similar approaches, indicating a potential for success in this area.
Where this research is happening
-
Nubad, LLC
Greer, United States Active
Researchers
- Principal investigator: Arya, Dev Priya — Nubad, LLC
- Study coordinator: Arya, Dev Priya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.