Creating new antibiotics using peptide nucleic acids

Development of peptide nucleic acid antibiotics-supplement 1

NIH-funded research Nubad, LLC · NIH-10835557

This study is working on creating new antibiotics that can better fight stubborn bacterial infections, especially for patients who have limited treatment options, by using special molecules to target the bacteria more effectively.

Quick facts

Grant typeNIH-funded research
Study typeNIH-funded research
Funding institutionNubad, LLC NIH-funded
Lab location1 site (Greer, United States)
Project IDNIH-10835557 on NIH RePORTER

What this research studies

This research focuses on developing innovative antibiotics that target bacterial infections by utilizing peptide nucleic acids. The project involves training a candidate in organic chemistry to explore novel chemical methods and biophysical techniques for synthesizing and testing these new antibacterial agents. By identifying compounds that bind to ribosomal RNA, the research aims to enhance the effectiveness of antibiotic therapies against resistant bacteria. Patients may benefit from new treatment options that are more effective against infections that currently have limited treatment alternatives.

Who could benefit from this research

Good fit: Ideal candidates for participation or benefit from this research would be individuals suffering from bacterial infections that are resistant to current antibiotic treatments.

Not a fit: Patients with viral infections or those who do not have antibiotic-resistant bacterial infections may not receive any benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to the development of new antibiotics that effectively combat antibiotic-resistant infections.

How similar studies have performed: Other research has shown promise in developing novel antibiotics using similar approaches, indicating a potential for success in this area.

Where this research is happening

Greer, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Infectious Disease PathwayInfectious DiseasesInfectious DisorderCommunicable Diseases
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.