Creating new antibiotics to fight resistant bacteria
Official title: Development of peptide nucleic acid antibiotics
Funded at Nubad, LLC · NIH-10762416 · Data updated 2026-11-12
This study is working on creating new antibiotics to help fight tough infections caused by a bacteria called Klebsiella pneumoniae, which can lead to serious lung problems, especially for patients who are already at risk.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Nubad, LLC NIH-funded |
| Lab location | 1 site (Greer, United States) |
| Project start | February 10, 2021 |
| Project end | January 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $998,585 |
| NIH project number | 5R42AI114114-05 |
| Project ID | NIH-10762416 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients with infections caused by Klebsiella pneumoniae or other resistant bacterial strains.
✕Less likely to help
Patients with viral infections that do not involve bacterial co-infections may not benefit from this research.
What this research studies
This research focuses on developing innovative peptide nucleic acid antibiotics to combat antimicrobial resistance, particularly against Klebsiella pneumoniae, a bacteria that can cause severe lung infections. The approach involves designing new classes of antibiotics that can effectively target and inhibit resistant bacterial strains. By addressing the urgent need for effective treatments against superbugs, this research aims to improve patient outcomes in the face of rising antibiotic resistance. Patients with bacterial infections, especially those at risk from viral lung infections, may benefit from these new antibiotics.
Why it matters
Potential benefit: If successful, this research could provide new treatment options for patients suffering from antibiotic-resistant bacterial infections.
How similar studies have gone: Other research has shown promise in developing new antibiotics to combat resistant bacteria, indicating that this approach has potential for success.
Where this research is happening
-
Nubad, LLC
Greer, United States Active
Researchers
- Principal investigator: Arya, Dev Priya — Nubad, LLC
- Study coordinator: Arya, Dev Priya
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.