Creating new algorithms to analyze molecular data in tissues
Developing novel algorithms for spatial molecular profiling technologies
['FUNDING_R01'] · UT SOUTHWESTERN MEDICAL CENTER · NIH-10834168
This study is looking at how genes and proteins behave in different parts of tissues to help us understand important processes like how embryos develop and how tumors can vary, which could lead to better ways to diagnose and treat health issues for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UT SOUTHWESTERN MEDICAL CENTER (nih funded) |
| Locations | 1 site (DALLAS, UNITED STATES) |
| Trial ID | NIH-10834168 on ClinicalTrials.gov |
What this research studies
This research focuses on developing advanced computational methods to analyze spatial molecular profiling data, which captures the location and abundance of mRNA and proteins in tissues. By studying gene expression across different locations, the research aims to uncover insights into critical biological processes such as embryo development and tumor heterogeneity. The project leverages recent technological advancements to enhance our understanding of cellular functions and their implications for health and disease. Patients may benefit from improved diagnostic and therapeutic strategies derived from a better understanding of molecular mechanisms.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions related to cellular and molecular dysfunctions, such as cancer or developmental disorders.
Not a fit: Patients with conditions unrelated to cellular or molecular processes may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments and diagnostics for various diseases by providing deeper insights into cellular functions.
How similar studies have performed: Other research has shown promise in using computational methods for analyzing complex biological data, indicating a strong potential for success in this novel approach.
Where this research is happening
DALLAS, UNITED STATES
- UT SOUTHWESTERN MEDICAL CENTER — DALLAS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: XIAO, GUANGHUA — UT SOUTHWESTERN MEDICAL CENTER
- Study coordinator: XIAO, GUANGHUA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.