NIH-funded research Sbir 2 grant

Creating new 3D printed microfluidic devices using PDMS.

Official title: ADDITIVE MANUFACTURING OF PDMS MICROFLUIDICS

Funded at Phase, INC. · NIH-10830468 · Data updated 2026-11-12

This study is working on creating better tiny models that act like human bodies to help test new medicines, using 3D printing to make them more effective and accurate for drug development.

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionPhase, INC.
NIH-funded
Lab location1 site (Cornelius, United States)
Project startApril 19, 2023
Project endMarch 31, 2026
Funding year2024
Award (this year)$764,258
NIH project number5R44TR003968-03
Project IDNIH-10830468 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals who are involved in or affected by conditions that require innovative therapeutic approaches, particularly those related to the blood-brain barrier and cardiovascular diseases.

Less likely to help

Patients with conditions that do not involve the blood-brain barrier or cardiovascular disorders may not receive direct benefits from this research.

What this research studies

This research focuses on developing advanced microfluidic models that can better mimic human biological systems for testing new therapeutics. By utilizing additive manufacturing, or 3D printing, the team aims to overcome the limitations of traditional manufacturing methods that restrict the design and functionality of microfluidic devices. The project seeks to innovate the use of polydimethylsiloxane (PDMS), a common material in microfluidics, by improving its 3D printing capabilities. This could lead to more accurate in vitro models that can enhance the drug development process.

Why it matters

Potential benefit: If successful, this research could lead to more effective and safer therapeutic options for patients by improving the drug testing process.

How similar studies have gone: While additive manufacturing in microfluidics is a growing field, this specific approach to enhancing PDMS printing is relatively novel and has not been widely tested.

Where this research is happening

  • Phase, INC.
    Cornelius, United States
    Active

Researchers

  • Principal investigator: Schultz, Jeffrey — Phase, INC.
  • Study coordinator: Schultz, Jeffrey

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
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Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.