Creating models to improve combination treatments for melanoma
PROJECT 2: Development and Refinement of Predictive Models for Designing Immunotherapy Combination Treatments
['FUNDING_OTHER'] · INSTITUTE FOR SYSTEMS BIOLOGY · NIH-10916309
This study is looking at ways to improve treatments for skin cancer by figuring out how cancer cells resist current therapies, so that patients can receive more personalized and effective combinations of immune therapies and targeted treatments.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | INSTITUTE FOR SYSTEMS BIOLOGY (nih funded) |
| Locations | 1 site (SEATTLE, UNITED STATES) |
| Trial ID | NIH-10916309 on ClinicalTrials.gov |
What this research studies
This research focuses on developing predictive models to enhance immunotherapy combination treatments for cutaneous melanoma. By understanding how cancer cells resist current therapies, the project aims to design more effective treatment regimens that combine immune-based strategies with targeted therapies. The approach involves using advanced techniques to analyze the tumor-immune microenvironment and how it influences treatment outcomes. Patients may benefit from more personalized and effective treatment options based on these models.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with cutaneous melanoma, particularly those who have shown resistance to existing therapies.
Not a fit: Patients with non-melanoma skin cancers or those who are not eligible for immunotherapy may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved survival rates and treatment effectiveness for melanoma patients.
How similar studies have performed: Other research has shown promise in using combination therapies for melanoma, indicating that this approach could lead to significant advancements in treatment.
Where this research is happening
SEATTLE, UNITED STATES
- INSTITUTE FOR SYSTEMS BIOLOGY — SEATTLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: THORSSON, VESTEINN — INSTITUTE FOR SYSTEMS BIOLOGY
- Study coordinator: THORSSON, VESTEINN
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.