Creating models to improve cancer treatment decisions using advanced cell analysis techniques
An informatics framework for single-cell multi-omics from clinical specimens
This study is looking at individual cells from cancer patients' biopsies to learn more about how tumors grow and change, so doctors can give more personalized treatment recommendations that fit each patient's unique cancer.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-11056108 on NIH RePORTER |
What this research studies
This research focuses on understanding the complexity of tumors by analyzing individual cells from patient biopsies. It aims to develop predictive models that combine new single-cell data with existing genomic information to help doctors make better treatment decisions. By using advanced techniques like single-cell RNA sequencing and spatial transcriptomics, the project seeks to identify how tumors evolve and respond to therapies. Ultimately, the goal is to provide personalized therapy recommendations based on the unique characteristics of each patient's cancer.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with various types of cancer, particularly those undergoing treatment decisions based on tumor characteristics.
Not a fit: Patients with non-cancerous conditions or those not undergoing treatment for cancer may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments for patients.
How similar studies have performed: Other research has shown promise in using single-cell analysis for cancer treatment, indicating that this approach could lead to significant advancements in precision oncology.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Diaz, Aaron Antonio — University of California, San Francisco
- Study coordinator: Diaz, Aaron Antonio
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.