Creating models of patient tumors for cancer treatment research
PDX Core
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA AT DAVIS · NIH-10896236
This study is creating special models using tumor samples from patients with gastric or lung cancers, especially from diverse backgrounds, to help researchers find better and more effective treatments for everyone.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA AT DAVIS (nih funded) |
| Locations | 1 site (DAVIS, UNITED STATES) |
| Trial ID | NIH-10896236 on ClinicalTrials.gov |
What this research studies
This research focuses on developing and characterizing Patient Derived Xenograft (PDX) models, which are created by implanting human tumor tissues into immune-deficient mice. The goal is to establish 120 PDX models from patients with gastric or lung cancers, particularly from racial and ethnic minorities. These models will help researchers study how different cancer treatments work and identify effective therapies tailored to diverse populations. By using these models, the research aims to address disparities in cancer treatment outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients diagnosed with gastric or lung cancers, particularly those from racial and ethnic minority groups.
Not a fit: Patients with cancers other than gastric or lung cancers may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments for patients from diverse backgrounds.
How similar studies have performed: Previous research using PDX models has shown promise in understanding cancer treatment responses, indicating that this approach is both tested and potentially impactful.
Where this research is happening
DAVIS, UNITED STATES
- UNIVERSITY OF CALIFORNIA AT DAVIS — DAVIS, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LLOYD, KC KENT — UNIVERSITY OF CALIFORNIA AT DAVIS
- Study coordinator: LLOYD, KC KENT
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Anti-Cancer Agents