Creating models of patient tumors for cancer treatment research
Official title: PDX Core
Funded at University of California at Davis · NIH-10896236 · Data updated 2026-11-12
This study is creating special models using tumor samples from patients with gastric or lung cancers, especially from diverse backgrounds, to help researchers find better and more effective treatments for everyone.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California at Davis NIH-funded |
| Lab location | 1 site (Davis, United States) |
| Project start | August 1, 2023 |
| Project end | July 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $175,219 |
| NIH project number | 5U54CA283766-02 |
| Project ID | NIH-10896236 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with gastric or lung cancers, particularly those from racial and ethnic minority groups.
✕Less likely to help
Patients with cancers other than gastric or lung cancers may not receive benefits from this research.
What this research studies
This research focuses on developing and characterizing Patient Derived Xenograft (PDX) models, which are created by implanting human tumor tissues into immune-deficient mice. The goal is to establish 120 PDX models from patients with gastric or lung cancers, particularly from racial and ethnic minorities. These models will help researchers study how different cancer treatments work and identify effective therapies tailored to diverse populations. By using these models, the research aims to address disparities in cancer treatment outcomes.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized cancer treatments for patients from diverse backgrounds.
How similar studies have gone: Previous research using PDX models has shown promise in understanding cancer treatment responses, indicating that this approach is both tested and potentially impactful.
Where this research is happening
-
University of California at Davis
Davis, United States Active
Researchers
- Principal investigator: Lloyd, Kc Kent — University of California at Davis
- Study coordinator: Lloyd, Kc Kent
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.