Creating long-lasting dental materials that resist decay

Hydrolysis-resistant resin networks for durable and multifunctional dental restorations

NIH-funded research Ada Forsyth Institute, INC. · NIH-10979230

This study is working on creating stronger and longer-lasting dental fillings that can better resist moisture and bacteria, so patients can enjoy healthier smiles with fewer trips to the dentist for replacements.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionAda Forsyth Institute, INC. NIH-funded
Lab location1 site (Cambridge, United States)
Project IDNIH-10979230 on NIH RePORTER

What this research studies

This research focuses on developing innovative dental restorations that are more durable and effective than current options. By formulating new resin networks that resist breakdown from moisture and bacteria, the project aims to enhance the longevity and performance of dental fillings. The approach includes testing these new materials in various conditions to ensure they can withstand the challenges of the oral environment. Patients can expect advancements in dental materials that may lead to fewer replacements and better oral health outcomes.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals who require dental restorations or fillings, particularly those at risk for dental decay.

Not a fit: Patients who have no need for dental restorations or those with allergies to the materials being tested may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to dental restorations that last significantly longer and reduce the incidence of secondary caries.

How similar studies have performed: Other research has shown promise in developing advanced dental materials, but this specific approach to hydrolysis-resistant resins is relatively novel.

Where this research is happening

Cambridge, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.