Creating long-lasting dental materials that resist decay
Official title: Hydrolysis-resistant resin networks for durable and multifunctional dental restorations
Funded at Ada Forsyth Institute, INC. · NIH-10979230 · Data updated 2026-11-12
This study is working on creating stronger and longer-lasting dental fillings that can better resist moisture and bacteria, so patients can enjoy healthier smiles with fewer trips to the dentist for replacements.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Ada Forsyth Institute, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project start | September 19, 2024 |
| Project end | June 30, 2029 |
| Funding year | 2024 |
| Award (this year) | $499,440 |
| NIH project number | 1R01DE033442-01A1 |
| Project ID | NIH-10979230 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who require dental restorations or fillings, particularly those at risk for dental decay.
✕Less likely to help
Patients who have no need for dental restorations or those with allergies to the materials being tested may not benefit from this research.
What this research studies
This research focuses on developing innovative dental restorations that are more durable and effective than current options. By formulating new resin networks that resist breakdown from moisture and bacteria, the project aims to enhance the longevity and performance of dental fillings. The approach includes testing these new materials in various conditions to ensure they can withstand the challenges of the oral environment. Patients can expect advancements in dental materials that may lead to fewer replacements and better oral health outcomes.
Why it matters
Potential benefit: If successful, this research could lead to dental restorations that last significantly longer and reduce the incidence of secondary caries.
How similar studies have gone: Other research has shown promise in developing advanced dental materials, but this specific approach to hydrolysis-resistant resins is relatively novel.
Where this research is happening
-
Ada Forsyth Institute, INC.
Cambridge, United States Active
Researchers
- Principal investigator: Sun, Jirun — Ada Forsyth Institute, INC.
- Study coordinator: Sun, Jirun
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.