Creating human organs in the lab using stem cells
Synthetic organogenesis: new paradigms in reconstituting human organ development in vitro
This study is exploring how to grow human organs in the lab using stem cells, which could help create better models for understanding diseases and testing new treatments, ultimately benefiting patients with advancements in organ regeneration and personalized medicine.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Columbia Univ New York Morningside NIH-funded |
| Lab location | 1 site (New York, United States) |
| Project ID | NIH-11173963 on NIH RePORTER |
What this research studies
This research investigates how to develop human organs in a laboratory setting by using stem cells to create 3D tissues that mimic the characteristics of real organs. The approach focuses on understanding the complex signals and interactions that guide the formation of organs during fetal development. By improving the methods used to create these organ-like structures, the research aims to produce more accurate models that can be used for studying diseases and testing treatments. Patients may benefit from advancements in organ regeneration and personalized medicine as a result of this work.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with conditions requiring organ transplants or those with genetic disorders affecting organ development.
Not a fit: Patients with stable organ function or those not requiring any form of organ replacement or regeneration may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in organ regeneration and the development of personalized treatments for various diseases.
How similar studies have performed: Other research has shown promise in developing organoids and using stem cells for organ development, indicating that this approach has potential for success.
Where this research is happening
New York, United States
- Columbia Univ New York Morningside — New York, United States (Active)
Researchers
- Principal investigator: Simunovic, Mijo — Columbia Univ New York Morningside
- Study coordinator: Simunovic, Mijo
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.