Creating human models to study lung adenocarcinoma
Official title: Human stem and progenitor-based models of lung adenocarcinoma
Funded at University of Illinois at Chicago · NIH-11041540 · Data updated 2026-11-12
This study is working on creating better models of lung adenocarcinoma, a common type of lung cancer, using samples from real patients to help researchers learn more about the disease and find more effective treatments just for you.
Quick facts
| Grant type | R03 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Illinois at Chicago NIH-funded |
| Lab location | 1 site (Chicago, UNITED STATES) |
| Project start | December 1, 2024 |
| Project end | November 30, 2026 |
| Funding year | 2025 |
| Award (this year) | $80,165 |
| NIH project number | 1R03CA289845-01A1 |
| Project ID | NIH-11041540 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are adults diagnosed with lung adenocarcinoma who are seeking innovative treatment options.
✕Less likely to help
Patients with other types of lung cancer or those who are not diagnosed with lung adenocarcinoma may not benefit from this research.
What this research studies
This research focuses on developing human-relevant models of lung adenocarcinoma, the most common subtype of non-small cell lung cancer. It aims to address the limitations of existing genetically engineered mouse models by utilizing patient-derived organoids and xenografts. These models will help researchers better understand the disease's biology and response to therapies, ultimately leading to more effective treatments. By studying the unique characteristics of human tumors, the research seeks to improve personalized medicine approaches for lung cancer patients.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with lung adenocarcinoma.
How similar studies have gone: Previous research has shown promise in using patient-derived models for cancer studies, indicating potential success for this novel approach.
Where this research is happening
-
University of Illinois at Chicago
Chicago, United States Active
Researchers
- Principal investigator: Kadur Lakshminarasim, Preetish — University of Illinois at Chicago
- Study coordinator: Kadur Lakshminarasim, Preetish
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.