Creating genetically engineered mice for food allergy research
Transgenic Core
This study is creating special mice to help us learn more about food allergies, which could lead to better treatments and ways to prevent them for people who suffer from these allergies.
Quick facts
| Grant type | P01 program project |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Food Allergy Science Initiative, INC. NIH-funded |
| Lab location | 1 site (Cambridge, United States) |
| Project ID | NIH-11088816 on NIH RePORTER |
What this research studies
This research focuses on developing genetically modified mice to better understand food allergies. The team will create various types of mice, including those with specific genes knocked out or modified, using advanced techniques like CRISPR. These engineered mice will help researchers study how different genes affect food allergies and the underlying mechanisms involved. The project aims to provide valuable insights that could lead to new treatments or preventive strategies for food allergies.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with food allergies or those interested in genetic studies related to allergic responses.
Not a fit: Patients without food allergies or those not interested in genetic research may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and management of food allergies, potentially resulting in new therapies for affected patients.
How similar studies have performed: Previous research using genetically engineered mice has shown promise in understanding various diseases, indicating that this approach could be effective for food allergy research as well.
Where this research is happening
Cambridge, United States
- Food Allergy Science Initiative, INC. — Cambridge, United States (Active)
Researchers
- Principal investigator: Lowell, Bradford B — Food Allergy Science Initiative, INC.
- Study coordinator: Lowell, Bradford B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.