Creating flexible brain implants with liquid metals

Engineering of Stretchable Neural Interfaces Using Liquid Metals for Stable Electrical Communication and Adaptive Stiffness Transformation

NIH-funded research University of Massachusetts Amherst · NIH-11174312

This project aims to develop new, soft brain implants using liquid metals to improve how they connect with brain tissue for long-term use.

Quick facts

Grant typeR21 grant
Study typeNIH-funded research
Funding institutionUniversity of Massachusetts Amherst NIH-funded
Lab location1 site (Hadley, United States)
Project IDNIH-11174312 on NIH RePORTER

What this research studies

Current brain implants can be too stiff, causing irritation and limiting how well they work over time. We are working on a new kind of implant that is soft and stretchable, much like brain tissue itself. These new implants will use special liquid metals combined with flexible materials to create a better connection. Our goal is to make these devices more stable and adaptable, allowing for clearer and longer-lasting communication with the brain. This could lead to a next-generation brain-computer interface.

Who could benefit from this research

Good fit: Patients who might benefit from future brain-computer interfaces for conditions like brain diseases or disorders could be ideal candidates for related research.

Not a fit: Patients not requiring or suitable for implantable neural devices would not directly benefit from this specific technology development.

Why it matters

Potential benefit: If successful, this work could lead to more effective and safer long-term brain-computer interfaces for people with brain diseases or disorders.

How similar studies have performed: While soft neural probes have been developed, this approach combining liquid metals and elastomers for improved stability and tunable stiffness is a novel direction.

Where this research is happening

Hadley, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Brain DiseasesBrain Disorders
Last reviewed 2026-06-09 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.