Creating digital tools to detect early signs of Alzheimer's disease
Development and validation of efficient cognitive composite scores of digital tools for the detection of early pathophysiological changes in Alzheimers disease
['FUNDING_CAREER'] · MASSACHUSETTS GENERAL HOSPITAL · NIH-10836540
This study is testing a new digital drawing tool to help spot early signs of Alzheimer's disease in people who are currently healthy, making it easier to identify those who might be at risk.
Quick facts
| Phase | ['FUNDING_CAREER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | MASSACHUSETTS GENERAL HOSPITAL (nih funded) |
| Locations | 1 site (BOSTON, UNITED STATES) |
| Trial ID | NIH-10836540 on ClinicalTrials.gov |
What this research studies
This research focuses on developing and validating digital tools that can efficiently assess cognitive changes associated with early Alzheimer's disease. By utilizing a digital clock drawing test, the study aims to capture detailed drawing outcomes and processes that correlate with underlying brain changes detected through advanced imaging techniques. The goal is to improve the detection of preclinical Alzheimer's in cognitively normal individuals, making it easier to identify those at risk. Participants will engage with these digital assessments, which are designed to be non-invasive and user-friendly.
Who could benefit from this research
Good fit: Ideal candidates for this research are cognitively normal older adults who may be at risk for developing Alzheimer's disease.
Not a fit: Patients with diagnosed Alzheimer's disease or significant cognitive impairment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of Alzheimer's disease, allowing for timely interventions.
How similar studies have performed: Other research has shown promise in using digital tools for cognitive assessment, indicating that this approach could be effective.
Where this research is happening
BOSTON, UNITED STATES
- MASSACHUSETTS GENERAL HOSPITAL — BOSTON, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FU, FANG LU (JESSIE) — MASSACHUSETTS GENERAL HOSPITAL
- Study coordinator: FU, FANG LU (JESSIE)
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Alzheimer disease dementia, Alzheimer syndrome