Creating devices to monitor heart responses to stress in aging animals
Developing insertable cardiac monitors to assess social and environmental effects on the autonomic stress response in a nonhuman primate model of aging
This study is looking at how stress from social situations and the environment impacts heart health in older monkeys, which can help us understand how early life experiences affect health later on, especially for conditions like obesity and diabetes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Notre Dame NIH-funded |
| Lab location | 1 site (Notre Dame, United States) |
| Project ID | NIH-11124496 on NIH RePORTER |
What this research studies
This research focuses on understanding how social and environmental stressors affect the heart and overall health in aging nonhuman primates. By developing advanced insertable cardiac monitors, the study aims to measure various stress responses, including those from the autonomic nervous system. The approach involves long-term observations of these animals to gather data on how early life experiences influence health outcomes later in life. This research could provide insights into the mechanisms behind chronic diseases like obesity and diabetes.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals interested in the effects of stress on health, particularly those with a history of chronic stress or related health conditions.
Not a fit: Patients who are not affected by stress-related health issues or those without a history of chronic stress may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of stress-related health issues in humans.
How similar studies have performed: Other research has shown success in using animal models to study stress responses, indicating that this approach is promising and not entirely novel.
Where this research is happening
Notre Dame, United States
- University of Notre Dame — Notre Dame, United States (Active)
Researchers
- Principal investigator: Archie, Elizabeth — University of Notre Dame
- Study coordinator: Archie, Elizabeth
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.