Creating detailed tissue maps to understand human pain
Spatial Core (Moffit)
This study is working on new ways to create detailed maps of cells in our tissues to better understand human pain, which could help improve treatments for people dealing with pain-related conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project ID | NIH-10928103 on NIH RePORTER |
What this research studies
This research focuses on developing advanced techniques to create detailed maps of tissues at the cellular level, specifically using a method called MERFISH. By analyzing the expression of thousands of different RNAs in individual cells, researchers aim to uncover new insights into the biology of human pain. The project addresses current technical challenges in implementing these methods and aims to make them more widely accessible for future studies. Patients may benefit from the findings as they could lead to better understanding and treatment of pain-related conditions.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals experiencing chronic pain or related disorders.
Not a fit: Patients with acute pain conditions or those not experiencing pain may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding and treating human pain.
How similar studies have performed: Other research has shown promise with similar spatial transcriptomic techniques, indicating potential for significant advancements in understanding complex biological systems.
Where this research is happening
Boston, United States
- Brigham and Women's Hospital — Boston, United States (Active)
Researchers
- Principal investigator: Moffitt, Jeffrey — Brigham and Women's Hospital
- Study coordinator: Moffitt, Jeffrey
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.