Creating detailed maps of cellular aging in human tissues
WU-SN-TMC Biospecimen Core
This study is looking at how aging cells behave in different parts of the body by collecting tissue samples from people of all ages, which will help us understand how these changes affect health and diseases related to aging.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Washington University NIH-funded |
| Lab location | 1 site (Saint Louis, United States) |
| Project ID | NIH-10914204 on NIH RePORTER |
What this research studies
This research focuses on understanding cellular senescence, a state of aging in cells that affects human health and disease. The Washington University Senescence Tissue Mapping Center will collect and analyze human tissue samples from various ages to create high-resolution atlases of cellular senescence across different tissue types, including bone marrow, breast, colon, and liver. By utilizing advanced multi-omics and imaging techniques, the project aims to generate valuable data that can inform both basic and translational research on aging and related diseases.
Who could benefit from this research
Good fit: Ideal candidates for participation include individuals of various ages who are undergoing procedures that allow for the collection of tissue samples, such as cosmetic surgeries or bone marrow donations.
Not a fit: Patients with chronic diseases or conditions that prevent them from providing tissue samples may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved understanding and treatment of age-related diseases and conditions.
How similar studies have performed: Other research has shown promise in using similar multi-omics approaches to study cellular aging, indicating potential for success in this novel initiative.
Where this research is happening
Saint Louis, United States
- Washington University — Saint Louis, United States (Active)
Researchers
- Principal investigator: Fields, Ryan C — Washington University
- Study coordinator: Fields, Ryan C
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.