NIH-funded research R03 grant

Creating detailed genetic maps for malaria-carrying mosquitoes

Official title: Development of high-quality reference genomes for Anopheles squamosus and An. cydippis

Funded at University of Florida · NIH-10846710 · Data updated 2026-11-12

This study is looking at the genes of two types of mosquitoes that spread malaria in southern Africa to find out how they might change the way they carry the disease and respond to insect sprays, which will help create better ways to fight malaria and protect people.

Quick facts

Grant typeR03 grant
Study typeNIH-funded research
Funding institutionUniversity of Florida
NIH-funded
Lab location1 site (Gainesville, United States)
Project startMay 23, 2023
Project endApril 30, 2026
Funding year2024
Award (this year)$62,270
NIH project number5R03AI178041-02
Project IDNIH-10846710 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research are individuals living in southern Africa who are at risk of malaria transmission due to the presence of these mosquito species.

Less likely to help

Patients who do not reside in southern Africa or who are not at risk of malaria transmission may not benefit from this research.

What this research studies

This research focuses on understanding the genetic makeup of two mosquito species, Anopheles squamosus and An. cydippis, which are important in the transmission of malaria in southern Africa. By producing high-quality reference genomes, the project aims to identify genetic variations that could influence how these mosquitoes transmit malaria and respond to insecticides. This information will help develop better diagnostic tools and control strategies against malaria-carrying mosquitoes, ultimately aiming to reduce malaria transmission in affected regions.

Why it matters

Potential benefit: If successful, this research could lead to improved methods for diagnosing and controlling malaria transmission, potentially saving lives in southern Africa.

How similar studies have gone: Previous research has successfully utilized genomic approaches to study mosquito vectors, indicating that this methodology has the potential for impactful results.

Where this research is happening

  • University of Florida
    Gainesville, United States
    Active

Researchers

  • Principal investigator: Lee, Yoosook — University of Florida
  • Study coordinator: Lee, Yoosook

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-14 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.