Creating detailed brain maps for humans and primates
A Multidisciplinary Center for Developing Human and Non-human Primate Brain Cell Atlases
This study is all about creating detailed maps of the brain for both people and monkeys to learn how different types of brain cells grow and work together over time, which could help us understand how the brain functions normally and what might go wrong in certain conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10918136 on NIH RePORTER |
What this research studies
This research aims to develop comprehensive brain atlases for both humans and non-human primates, focusing on understanding the diversity of brain cell types and their development over time. By analyzing brain samples from various stages of development, including mid-gestation, neonatal, childhood, and adolescence, the researchers will use advanced techniques like single nucleus RNA sequencing and spatial transcriptomics to map out the cellular and anatomical features of the brain. This work will help uncover how different brain regions develop and interact, providing insights into normal brain function and potential disorders.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with autism spectrum disorder (ASD) and those interested in brain development across different ages.
Not a fit: Patients with stable neurological conditions unrelated to brain development may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of brain development and its implications for conditions like autism and other neurological disorders.
How similar studies have performed: Previous research has shown success in mapping brain structures and functions, indicating that this approach has the potential for significant breakthroughs in understanding brain development.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Kriegstein, Arnold — University of California, San Francisco
- Study coordinator: Kriegstein, Arnold
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.