Creating detailed brain maps for humans and primates
A Multidisciplinary Center for Developing Human and Non-human Primate Brain Cell Atlases
This study is all about creating detailed maps of the brain for both people and monkeys to learn how different types of brain cells grow and change over time, which could help us understand brain disorders better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of California, San Francisco NIH-funded |
| Lab location | 1 site (San Francisco, United States) |
| Project ID | NIH-10835480 on NIH RePORTER |
What this research studies
This research aims to develop comprehensive brain atlases for both humans and non-human primates, focusing on understanding the diversity of brain cell types and their development over time. By analyzing brain samples from various developmental stages, including mid-gestation, neonatal, childhood, and adolescence, the researchers will use advanced techniques like single nucleus RNA sequencing and spatial transcriptomics to map out the cellular and anatomical features of the brain. This work will help uncover how different brain regions develop and interact, providing insights into brain disorders and diseases.
Who could benefit from this research
Good fit: Ideal candidates for participation or benefit from this research include individuals with autism spectrum disorder (ASD) and those at various developmental stages from mid-gestation to adolescence.
Not a fit: Patients with fully developed brains or those outside the specified age range may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to a better understanding of brain development and its implications for conditions like autism and other brain disorders.
How similar studies have performed: Other research has shown success in mapping brain structures and functions, but this approach aims to provide unprecedented detail and is considered innovative in its methodology.
Where this research is happening
San Francisco, United States
- University of California, San Francisco — San Francisco, United States (Active)
Researchers
- Principal investigator: Kriegstein, Arnold — University of California, San Francisco
- Study coordinator: Kriegstein, Arnold
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.