Creating detailed 4D models of blood vessels in the brain for better treatment of neurovascular diseases
Official title: Generating High Quality, High Resolution, Patient-Specific 4D Models of Cerebral Vasculature
Funded at Brigham and Women's Hospital · NIH-11051237 · Data updated 2026-11-12
This study is creating detailed 3D models of blood vessels in the brain to help doctors better understand and treat conditions like strokes and aneurysms, using advanced imaging techniques to make personalized treatment plans just for you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | April 1, 2023 |
| Project end | March 31, 2027 |
| Funding year | 2025 |
| Award (this year) | $362,475 |
| NIH project number | 5R01EB034223-03 |
| Project ID | NIH-11051237 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals diagnosed with neurovascular conditions such as stroke, aneurysms, or arteriovenous malformations.
✕Less likely to help
Patients with neurovascular diseases who are not candidates for surgical intervention or those with conditions not addressed by this research may not benefit.
What this research studies
This research focuses on developing high-quality, patient-specific 4D models of cerebral vasculature to improve the understanding and treatment of neurovascular diseases such as stroke and aneurysms. By utilizing advanced imaging techniques, specifically Digital Subtraction Angiography (DSA), the project aims to generate detailed representations of blood vessels that can be used both before and during surgical procedures. The approach involves extracting and annotating data from 2D DSA images to create these comprehensive models, which could lead to more effective treatment strategies tailored to individual patients.
Why it matters
Potential benefit: If successful, this research could significantly enhance the precision of treatments for patients suffering from neurovascular diseases, potentially improving outcomes and reducing risks during surgery.
How similar studies have gone: Previous research has shown promise in using advanced imaging techniques for similar applications, indicating a potential for success in this novel approach.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Frisken, Sarah — Brigham and Women's Hospital
- Study coordinator: Frisken, Sarah
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.