Creating detailed 3D models of mouse embryo development
Official title: Towards Foundational 3D In Silico Models of Whole Mouse Embryogenesis
Funded at Stanford University · NIH-10910636 · Data updated 2026-11-12
This study is creating detailed computer models to understand how mouse embryos develop, which could help researchers learn more about human development and related health issues in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Stanford University NIH-funded |
| Lab location | 1 site (Stanford, United States) |
| Project start | September 19, 2024 |
| Project end | August 31, 2027 |
| Funding year | 2024 |
| Award (this year) | $1,312,485 |
| NIH project number | 1DP2HG014282-01 |
| Project ID | NIH-10910636 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals interested in developmental biology or those affected by congenital conditions.
✕Less likely to help
Patients with conditions unrelated to embryonic development or those not interested in research on developmental biology may not receive benefits from this research.
What this research studies
This research aims to develop advanced 3D in silico models that simulate the entire process of mouse embryogenesis. By utilizing innovative sequencing technologies and machine learning techniques, the project will create a comprehensive cell atlas that captures the development of mouse embryos at a single-cell level over time. This approach will allow researchers to analyze complex biological processes and make predictions about embryonic development. Patients may benefit from insights gained through this research, which could inform future studies on human development and related conditions.
Why it matters
Potential benefit: If successful, this research could enhance our understanding of embryonic development and lead to breakthroughs in treating developmental disorders.
How similar studies have gone: Previous research has shown success in creating models of simpler organisms, but this approach to whole mammalian embryogenesis is novel and untested.
Where this research is happening
-
Stanford University
Stanford, United States Active
Researchers
- Principal investigator: Qiu, Xiaojie — Stanford University
- Study coordinator: Qiu, Xiaojie
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.