Creating detailed 3D maps of human organs to understand their function
Multi-omic 3D tissue maps for a Human BioMolecular Atlas
This study is working on creating detailed 3D maps of human organs to see how the way tissues are organized affects how cells work, which could help us understand diseases like diabetes better and lead to better ways to diagnose and treat them.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Battelle Pacific Northwest Laboratories NIH-funded |
| Lab location | 1 site (Richland, United States) |
| Project ID | NIH-10685583 on NIH RePORTER |
What this research studies
This research aims to develop high-resolution, three-dimensional maps of human organs to better understand how tissue organization affects cell function in both healthy and diseased states. By utilizing advanced techniques like mass spectrometry and multiplexed imaging, the project seeks to create comprehensive biomolecular maps that reveal the complex interactions within tissues. This approach will help identify unknown biomolecular targets and improve our understanding of various diseases, including diabetes. Patients may benefit from insights gained through these maps, which could lead to improved diagnostics and treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions affecting organ function, such as diabetes or other metabolic disorders.
Not a fit: Patients with stable, non-progressive conditions that do not affect organ function may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to breakthroughs in understanding organ function and disease mechanisms, ultimately improving patient care and treatment options.
How similar studies have performed: Other research has shown promise in using multi-omic approaches for tissue mapping, indicating potential for success in this novel application.
Where this research is happening
Richland, United States
- Battelle Pacific Northwest Laboratories — Richland, United States (Active)
Researchers
- Principal investigator: Qian, Wei-Jun — Battelle Pacific Northwest Laboratories
- Study coordinator: Qian, Wei-Jun
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.