Creating computer models to understand radical chemistry
Official title: Computational Models for New Developments in Radical Chemistry
Funded at Colorado State University · NIH-10907794 · Data updated 2026-11-12
This study is exploring new ways to understand how certain tiny particles behave during chemical reactions, which could help create better tools for making medicines and other important chemicals, ultimately benefiting patients like you.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Colorado State University NIH-funded |
| Lab location | 1 site (Fort Collins, United States) |
| Project start | September 1, 2023 |
| Project end | June 30, 2027 |
| Funding year | 2024 |
| Award (this year) | $304,186 |
| NIH project number | 5R01GM151533-02 |
| Project ID | NIH-10907794 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for benefiting from this research include individuals with conditions that could be treated using novel chemical compounds developed through these advanced models.
✕Less likely to help
Patients who are not affected by conditions treatable with new chemical therapies may not receive direct benefits from this research.
What this research studies
This research focuses on developing advanced computational models to predict how organic radicals and diradicals behave during chemical reactions. By leveraging machine learning and computational techniques, the project aims to uncover new pathways for chemical transformations that are not possible in traditional states. The goal is to enhance the design of catalysts and reagents that can facilitate these reactions, particularly in a way that is selective and efficient. Patients may benefit indirectly through advancements in medicinal chemistry and drug development that arise from these findings.
Why it matters
Potential benefit: If successful, this research could lead to more effective and targeted therapies in medicinal chemistry.
How similar studies have gone: While the approach of using computational models in chemistry is established, the specific focus on radical chemistry and its applications is relatively novel and has shown promise in preliminary studies.
Where this research is happening
-
Colorado State University
Fort Collins, United States Active
Researchers
- Principal investigator: Paton, Robert Scott — Colorado State University
- Study coordinator: Paton, Robert Scott
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.