Creating complex 3D models of cells and tissues
Building biophysical and biochemical complexity in 3D cell and tissue constructs
This study is all about creating special 3D models of cells and tissues that look and act like they do in the body, helping researchers learn how cells work and respond to their environment, which could lead to better treatments for diseases and improvements in organ transplants.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Virginia NIH-funded |
| Lab location | 1 site (Charlottesville, United States) |
| Project ID | NIH-10927246 on NIH RePORTER |
What this research studies
This research focuses on developing advanced 3D cell and tissue constructs that mimic the natural environments of cells. By using innovative biofabrication technologies, the project aims to enhance our understanding of how cells interact and respond to their surroundings, which is crucial for addressing various biomedical challenges. The methodology involves systematically building and modifying these constructs to study cellular behaviors and disease progression, potentially leading to breakthroughs in tissue engineering and organ transplantation.
Who could benefit from this research
Good fit: Ideal candidates for this research are adults who may benefit from advancements in tissue engineering or organ transplantation.
Not a fit: Patients who are not adults or those not facing issues related to organ transplants or tissue engineering may not receive benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to improved tissue engineering techniques that may help patients awaiting organ transplants.
How similar studies have performed: Previous research in biofabrication has shown promising results in creating complex tissue constructs, indicating that this approach has potential for success.
Where this research is happening
Charlottesville, United States
- University of Virginia — Charlottesville, United States (Active)
Researchers
- Principal investigator: Highley, Christopher B — University of Virginia
- Study coordinator: Highley, Christopher B
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.