Creating better ways to diagnose lung disease after tuberculosis in Uganda
Official title: Improving Diagnostic Strategies for Post-Tuberculosis Lung Disease in Ugandan Primary Healthcare Settings
Funded at Mbarara University/science/ Technology · NIH-10973664 · Data updated 2026-11-12
This study is working on a new tool to help doctors in Uganda spot lung problems that can happen after someone has had tuberculosis, making sure they get the care they need to feel better.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Mbarara University/science/ Technology NIH-funded |
| Lab location | 1 site (Mbarara, Uganda) |
| Project start | September 1, 2024 |
| Project end | August 31, 2029 |
| Funding year | 2024 |
| Award (this year) | $108,237 |
| NIH project number | 1K43TW012781-01 |
| Project ID | NIH-10973664 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals over 21 years old who have a history of tuberculosis and are experiencing respiratory symptoms.
✕Less likely to help
Patients who have not had tuberculosis or do not exhibit respiratory symptoms may not benefit from this research.
What this research studies
This research aims to develop a diagnostic tool for identifying post-tuberculosis lung disease in primary healthcare settings in Uganda. It focuses on understanding the knowledge and attitudes of health workers regarding this condition, which is often overlooked after tuberculosis treatment. The project will involve creating a clinical diagnostic algorithm based on patient history and physical examinations, making it accessible for use in low-resource environments. By addressing the gap in post-TB care, the research seeks to improve the quality of life for patients who have survived tuberculosis.
Why it matters
Potential benefit: If successful, this research could lead to improved diagnosis and management of chronic lung disease in tuberculosis survivors, enhancing their quality of life.
How similar studies have gone: While the approach of developing diagnostic tools for post-TB lung disease is innovative, similar studies have shown promise in improving healthcare outcomes in low-resource settings.
Where this research is happening
-
Mbarara University/science/ Technology
Mbarara, Uganda Active
Researchers
- Principal investigator: Nuwagira, Edwin — Mbarara University/science/ Technology
- Study coordinator: Nuwagira, Edwin
Related research
Other NIH-funded projects on the same topics.
-
Coronary disease and immune activation in people with HIV and tuberculosis coinfection
This research looks at how having HIV and latent tuberculosis together might raise the risk of heart disease, and what immune changes are involved.
-
Pulmonary rehabilitation to reduce breathing problems after tuberculosis
A program of guided exercise and breathing training to help adults who have recovered from TB breathe better and feel healthier.
-
Pulmonary rehab to reduce breathing troubles after TB
A program of pulmonary rehabilitation is being studied to help adults who have completed TB treatment avoid ongoing lung problems and improve daily breathing.
-
Air pollution and tuberculosis spread in Kampala, Uganda
This project looks at whether dirty air from PM2.5 particles makes tuberculosis more likely to spread within urban slum households in Kampala, Uganda.
-
Air pollution and TB spread in Ugandan urban slums
This project explores whether exposure to air pollution makes tuberculosis more likely to spread within households in a crowded Ugandan slum.
-
Air pollution and TB transmission in Kampala’s urban slums
This project looks at whether air pollution from PM2.5 makes tuberculosis spread more easily from infected people to their neighbors in urban slums of Kampala, Uganda.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.