Creating better treatment options for young people living with HIV
Designing Next Generation Treatment Strategies for Adolescents and Young Adults Living with HIV (The NextGen Study)
This study is looking to find the best ways to help young people with HIV in South Africa stick to their treatment by talking to them, their parents, and doctors about what works for them, and it will let participants aged 18-29 try out different medication options to see which ones they prefer and how well they help.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Johns Hopkins University NIH-funded |
| Lab location | 1 site (Baltimore, United States) |
| Project ID | NIH-10906912 on NIH RePORTER |
What this research studies
This research aims to develop tailored antiretroviral therapy (ART) strategies for adolescents and young adults living with HIV in South Africa. By conducting interviews with youth, parents, and healthcare providers, the study seeks to identify barriers to treatment and preferences for long-acting injectables (LAIs) versus standard oral medications. Participants aged 18-29 will have the opportunity to choose between different treatment options in a pilot trial, with follow-up to assess the effectiveness of these strategies in improving adherence and health outcomes.
Who could benefit from this research
Good fit: Ideal candidates for this research are adolescents and young adults aged 12-29 living with HIV, particularly those in South Africa.
Not a fit: Patients who are not living with HIV or are outside the age range of 12-29 may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized HIV treatment options for young people, improving their health and quality of life.
How similar studies have performed: Previous research has shown that preference-driven treatment strategies can improve adherence and health outcomes in similar populations, indicating potential success for this approach.
Where this research is happening
Baltimore, United States
- Johns Hopkins University — Baltimore, United States (Active)
Researchers
- Principal investigator: Schwartz, Sheree Renae — Johns Hopkins University
- Study coordinator: Schwartz, Sheree Renae
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.