Creating better guidelines for identifying and treating sepsis in patients.
Developing Evidence-Based Sepsis Time Zero Criteria and Quality Metrics Using Electronic Health Record Data
['FUNDING_R01'] · HARVARD PILGRIM HEALTH CARE, INC. · NIH-10840316
This study is looking at how to better spot and treat sepsis, a serious condition, by using health records to create clearer guidelines for when to start treatment, so that only those who really need it get antibiotics and others can avoid unnecessary risks.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | HARVARD PILGRIM HEALTH CARE, INC. (nih funded) |
| Locations | 1 site (Canton, UNITED STATES) |
| Trial ID | NIH-10840316 on ClinicalTrials.gov |
What this research studies
This research focuses on improving the identification and treatment of sepsis, a life-threatening condition. By analyzing electronic health record data, the project aims to develop clearer criteria for when to start treatment, which could help avoid unnecessary antibiotic use in patients who do not have sepsis. The goal is to enhance patient outcomes by ensuring that only those who truly need immediate treatment receive it, while also minimizing the risks associated with aggressive antibiotic therapy. This approach seeks to refine the current guidelines that often lead to over-treatment.
Who could benefit from this research
Good fit: Ideal candidates for this research are patients who present with symptoms suggestive of sepsis but may not necessarily have the condition.
Not a fit: Patients who are already diagnosed with sepsis and require immediate treatment may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate treatment protocols for sepsis, reducing unnecessary antibiotic use and improving patient safety.
How similar studies have performed: Previous research has shown that refining treatment protocols based on specific clinical presentations can lead to improved patient outcomes, indicating that this approach has potential for success.
Where this research is happening
Canton, UNITED STATES
- HARVARD PILGRIM HEALTH CARE, INC. — Canton, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: RHEE, CHANU — HARVARD PILGRIM HEALTH CARE, INC.
- Study coordinator: RHEE, CHANU
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.