Creating artificial RNA structures to control and monitor cellular processes
Developing synthetic RNA organelles for spatiotemporal separation, control, and monitoring in living cells
['FUNDING_OTHER'] · UNIVERSITY OF CALIFORNIA LOS ANGELES · NIH-10951551
This study is exploring how to create special RNA structures that can help scientists control and monitor what happens inside living cells, which could lead to new ways to treat diseases and improve our understanding of how cells work.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF CALIFORNIA LOS ANGELES (nih funded) |
| Locations | 1 site (LOS ANGELES, UNITED STATES) |
| Trial ID | NIH-10951551 on ClinicalTrials.gov |
What this research studies
This research focuses on developing synthetic RNA organelles that can separate, control, and monitor activities within living cells. By utilizing engineered RNA instead of proteins, the project aims to create artificial condensates that can be programmed for specific interactions, allowing for precise manipulation of cellular functions. These RNA structures are designed to be low in toxicity and easily transferable across different organisms, potentially leading to innovative applications in cellular biology and medicine.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with conditions that involve cellular dysfunction or require advanced therapeutic interventions.
Not a fit: Patients with stable conditions that do not involve cellular manipulation or dysfunction may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to new methods for controlling cellular processes, which may improve treatments for various diseases.
How similar studies have performed: While the concept of using RNA for cellular applications is emerging, this specific approach of creating artificial RNA organelles is relatively novel and has not been extensively tested in prior research.
Where this research is happening
LOS ANGELES, UNITED STATES
- UNIVERSITY OF CALIFORNIA LOS ANGELES — LOS ANGELES, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: FRANCO, ELISA — UNIVERSITY OF CALIFORNIA LOS ANGELES
- Study coordinator: FRANCO, ELISA
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.