Creating antibodies to study tuberculosis in guinea pigs
Official title: Development of Monoclonal Antibodies for the Study of Mycobacterium tuberculosis (Mtb) in the Guinea Pig
Funded at Glycoscientific, LLC · NIH-10933281 · Data updated 2026-11-12
This study is looking at how tuberculosis spreads and affects the body by creating special tools to see how guinea pigs' immune systems respond to the disease, which could help us find better ways to diagnose and treat TB in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Glycoscientific, LLC NIH-funded |
| Lab location | 1 site (Athens, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $600,000 |
| NIH project number | 75N93023C00038-0-9999-1 |
| Project ID | NIH-10933281 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals who are at risk of tuberculosis infection or have been diagnosed with TB.
✕Less likely to help
Patients who do not have tuberculosis or are not at risk for the disease may not benefit from this research.
What this research studies
This research focuses on developing specific antibodies for six inflammatory cytokines to better understand how tuberculosis (TB) is transmitted and how the disease develops in guinea pigs. By producing these antibodies, researchers will evaluate the immune responses in both TB-infected and non-infected guinea pigs. This work aims to enhance our knowledge of the immune system's reaction to TB, which could lead to improved diagnostics and treatments for the disease.
Why it matters
Potential benefit: If successful, this research could lead to better understanding and management of tuberculosis, potentially improving treatment options for patients.
How similar studies have gone: Other research has shown success in using monoclonal antibodies to study infectious diseases, indicating that this approach has potential.
Where this research is happening
-
Glycoscientific, LLC
Athens, United States Active
Researchers
- Principal investigator: Popov, Marla — Glycoscientific, LLC
- Study coordinator: Popov, Marla
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.