Creating antibodies to study long-COVID in hamsters
Affinity Reagents for the Immune System of Golden Hamster (for SARS-CoV-2 induced long-COVID disease)
['FUNDING_OTHER'] · QOOLABS, INC. · NIH-10933277
This study is looking to create special antibodies that can help researchers learn more about how the immune system responds to long-COVID in hamsters, which could eventually help us understand the condition better for everyone.
Quick facts
| Phase | ['FUNDING_OTHER'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | QOOLABS, INC. (nih funded) |
| Locations | 1 site (Carlsbad, UNITED STATES) |
| Trial ID | NIH-10933277 on ClinicalTrials.gov |
What this research studies
This research focuses on developing high-affinity monoclonal antibodies targeting specific immune cells in Syrian golden hamsters, which are important for understanding long-COVID. The approach involves immunizing rabbits with specially designed proteins to produce these antibodies. Once generated, the antibodies will be validated for their effectiveness in studying long-COVID in hamster models infected with SARS-CoV-2. This work aims to enhance our understanding of the immune response related to long-COVID.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals experiencing long-COVID symptoms and those interested in the underlying immune mechanisms.
Not a fit: Patients who do not have long-COVID or are not affected by SARS-CoV-2 may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to better diagnostic tools and treatments for long-COVID by providing insights into immune responses.
How similar studies have performed: Other research has shown promise in using monoclonal antibodies for studying immune responses, indicating that this approach could be effective.
Where this research is happening
Carlsbad, UNITED STATES
- QOOLABS, INC. — Carlsbad, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: QI, HONG — QOOLABS, INC.
- Study coordinator: QI, HONG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Disorder