Creating antibodies to study immune responses in less common animal models
Official title: Reagents for Immunologic Analysis of Under-represented Mammalian Models
Funded at Integral Molecular · NIH-10933278 · Data updated 2026-11-12
This study is working on creating special antibodies to help scientists learn more about how the immune system works in certain animals that are similar to humans, which could lead to better treatments for diseases that affect us.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Integral Molecular NIH-funded |
| Lab location | 1 site (Philadelphia, United States) |
| Project start | September 1, 2023 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $600,000 |
| NIH project number | 75N93023C00036-0-9999-1 |
| Project ID | NIH-10933278 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research would include individuals with conditions that are being studied in relation to immune function and responses.
✕Less likely to help
Patients with conditions unrelated to immune function or those who do not have access to the specific animal models being studied may not receive any benefit from this research.
What this research studies
This research focuses on developing a wide range of monoclonal antibodies that can react with immune cell markers in nine underrepresented mammalian models. By generating these antibodies, the research aims to enhance the understanding of immune function and responses in these animals, which share similarities with human immunity. This could lead to better insights into various human diseases by utilizing these animal models more effectively. Patients may benefit from improved treatments and therapies derived from this enhanced understanding of immune responses.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in understanding and treating human diseases by utilizing underrepresented animal models.
How similar studies have gone: Other research has shown success in using monoclonal antibodies to study immune responses, indicating that this approach is promising and not entirely novel.
Where this research is happening
-
Integral Molecular
Philadelphia, United States Active
Researchers
- Principal investigator: Chambers, Ross — Integral Molecular
- Study coordinator: Chambers, Ross
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Creating faster and safer tests for viruses like COVID-19
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.