Creating and testing gene-edited pigs for human health research
Official title: Resource: Swine Somatic Cell Gene Editing Testing Center
Funded at University of Missouri-Columbia · NIH-10928247 · Data updated 2026-11-12
This study is using specially modified pigs to help us learn more about human diseases and test new treatments, so we can find better ways to help people with these conditions.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | University of Missouri-Columbia NIH-funded |
| Lab location | 1 site (Columbia, United States) |
| Project start | September 12, 2023 |
| Project end | August 31, 2028 |
| Funding year | 2024 |
| Award (this year) | $270,601 |
| NIH project number | 5U42OD035738-02 |
| Project ID | NIH-10928247 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for participation or benefit from this research include individuals with genetic conditions that could be modeled in swine.
✕Less likely to help
Patients with conditions that do not have a corresponding swine model or those not interested in genetic research may not benefit from this research.
What this research studies
This research focuses on developing and utilizing genetically modified pigs as models to study human diseases and evaluate new gene editing technologies. The team will produce, import, and maintain these swine models, ensuring they are cryopreserved and validated for research purposes. By mimicking human genetic conditions, these pigs will help assess the therapeutic potential of novel treatments and gene editing approaches. The project aims to enhance our understanding of disease mechanisms and improve therapeutic strategies.
Why it matters
Potential benefit: If successful, this research could lead to significant advancements in gene therapy and treatments for human diseases.
How similar studies have gone: Previous research has shown promise in using animal models for gene editing, indicating that this approach could yield valuable insights.
Where this research is happening
-
University of Missouri-Columbia
Columbia, United States Active
Researchers
- Principal investigator: Prather, Randall S — University of Missouri-Columbia
- Study coordinator: Prather, Randall S
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.