Creating and storing 3D-printed tissue for medical use
Official title: Cryobioprinting for Shelf-Ready Tissue Fabrication and Storage
Funded at Brigham and Women's Hospital · NIH-10927669 · Data updated 2026-11-12
This study is exploring a new way to create and store living tissue using a special printing technique that keeps the tissues safe for a long time, which could help patients needing organ replacements or other medical treatments in the future.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 19, 2023 |
| Project end | September 18, 2025 |
| Funding year | 2023 |
| Award (this year) | $499,342 |
| NIH project number | 1R56EB034702-01 |
| Project ID | NIH-10927669 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals needing tissue grafts or organ replacements due to injury, disease, or congenital conditions.
✕Less likely to help
Patients with conditions that do not require tissue engineering or organ replacement may not benefit from this research.
What this research studies
This research focuses on developing a new method called cryobioprinting, which combines 3D bioprinting with cryopreservation to create and store cell-laden tissue constructs. By using specially designed bioinks and a controlled freezing process, the researchers aim to fabricate intricate tissue structures that can be preserved for long-term use. This approach addresses current challenges in the bioprinting field, particularly the difficulties in storing these constructs for future medical applications. Patients may benefit from advancements in tissue engineering and organ replacement therapies as a result of this innovative technique.
Why it matters
Potential benefit: If successful, this research could lead to the availability of ready-to-use, bioprinted tissues for transplantation and regenerative medicine.
How similar studies have gone: While the concept of bioprinting is established, the specific approach of cryobioprinting for long-term storage is relatively novel and has not been extensively tested in clinical settings.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Zhang, Y. Shrike — Brigham and Women's Hospital
- Study coordinator: Zhang, Y. Shrike
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.