Creating and banking cell lines and serum samples for muscular dystrophy research

Who could benefit from this research

What this research studies

This research focuses on developing and banking cell lines and serum samples from individuals with muscular dystrophy to facilitate the study of genetic therapies. By using a technique that transforms skin cells into muscle-like cells, researchers aim to overcome challenges associated with obtaining muscle cells through invasive biopsies. The project will expand the collection of these unique cell lines and serum samples, which will be used for various collaborative research efforts aimed at improving treatment options for muscular dystrophy patients.

Why it matters

Where this research is happening

• Research Inst Nationwide Children's Hosp
  Columbus, United States Active

Researchers

• Principal investigator: Wein, Nicolas — Research Inst Nationwide Children's Hosp
• Study coordinator: Wein, Nicolas

Related research

Other NIH-funded projects on the same topics.

• Advancing manufacturing and release testing for a Duchenne gene editing therapy

  A project to optimize how a dual-vector AAV gene editing treatment for Duchenne muscular dystrophy is made and tested, so it can move toward clinical use.

  NIH research Myogene Bio, LLC · San Diego, UNITED STATES · NIH-11526941

• Understanding why Duchenne Muscular Dystrophy worsens and how to stop it

  A research team at USC is studying Duchenne muscular dystrophy to find out why the disease continues to progress and how to interrupt harmful changes in muscle tissue.

  NIH research University of Southern California · Los Angeles, UNITED STATES · NIH-11502706

• Endocrine role of intramuscular fat in muscular dystrophy

  This grant studies how fat that builds up inside muscles in Duchenne and Becker muscular dystrophy may release hormones that affect overall health, especially metabolism.

  NIH research University of Florida · Gainesville, United States · NIH-11460264

• Stopping steroid-related muscle and bone wasting in Duchenne muscular dystrophy

  Researchers are testing ways to protect muscles and bones in people with Duchenne muscular dystrophy who take long-term steroid medicines.

  NIH research Univ of Arkansas for Med Scis · Little Rock, United States · NIH-11458914

• Curation of muscular dystrophy genes to improve diagnosis and care

  A grant to help doctors better interpret genetic tests for muscular dystrophy and myopathy so patients get clearer diagnoses and faster access to therapies.

  NIH research Washington University · Saint Louis, United States · NIH-11417940

• MR clues to how nNOS affects energy use and blood flow in Becker and Duchenne muscular dystrophy

  This project looks at how advanced MRI tests can track muscle energy and blood flow changes in people with Becker and Duchenne muscular dystrophy as new gene therapies are explored.

  NIH research University of Florida · Gainesville, United States · NIH-11413866

About this research

1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.