Creating advanced Vitamin B6-based antioxidants to reduce chronic inflammation
Official title: Engineering hydrophilic/amphiphilic Vitamin B6-based super antioxidant dendrimers for controlling chronic inflammation
Funded at Central Michigan University · NIH-10798901 · Data updated 2026-11-12
This study is exploring new Vitamin B6-based molecules that could help reduce inflammation, which might lead to better treatments for conditions like arthritis, asthma, and heart disease, and it's being done at Central Michigan University.
Quick facts
| Grant type | R15 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Central Michigan University NIH-funded |
| Lab location | 1 site (Mount Pleasant, United States) |
| Project start | September 1, 2022 |
| Project end | August 31, 2025 |
| Funding year | 2023 |
| Award (this year) | $100,000 |
| NIH project number | 3R15GM147862-01S1 |
| Project ID | NIH-10798901 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research include individuals suffering from chronic inflammatory conditions such as arthritis, asthma, or cardiovascular diseases.
✕Less likely to help
Patients with acute inflammatory conditions or those not affected by chronic inflammation may not benefit from this research.
What this research studies
This research focuses on developing innovative Vitamin B6-based dendrimers, which are specialized molecules designed to act as powerful antioxidants. By utilizing advanced techniques like Electrospray Ionization Mass Spectrometry, the team will accurately measure the molecular weights of these dendrimers to ensure their effectiveness in controlling chronic inflammation. Patients may benefit from this research as it aims to create new treatments for conditions like arthritis, asthma, and cardiovascular diseases. The project is being conducted at Central Michigan University, where the necessary equipment will enhance the efficiency of the synthesis process.
Why it matters
Potential benefit: If successful, this research could lead to new antioxidant treatments that significantly reduce chronic inflammation in patients.
How similar studies have gone: Previous research has shown promise in using dendrimers for therapeutic applications, indicating potential success for this novel approach.
Where this research is happening
-
Central Michigan University
Mount Pleasant, United States Active
Researchers
- Principal investigator: Lee, Choon Young — Central Michigan University
- Study coordinator: Lee, Choon Young
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.