Creating advanced treatments for head and neck cancer using implantable devices
Official title: Development and optimization of highly effective treatments in patients with head and neck cancer using in situ implantable microdevices
Funded at Brigham and Women's Hospital · NIH-11027024 · Data updated 2026-11-12
This study is testing new tiny devices that can deliver cancer treatments right to tumors in people with head and neck cancer, helping doctors find the best options for each patient while aiming to improve results and lessen side effects.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Brigham and Women's Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | December 13, 2024 |
| Project end | November 30, 2029 |
| Funding year | 2025 |
| Award (this year) | $703,540 |
| NIH project number | 1R01CA295683-01 |
| Project ID | NIH-11027024 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with head and neck cancer who are seeking personalized treatment options.
✕Less likely to help
Patients with cancers other than head and neck cancer may not benefit from this specific research.
What this research studies
This research focuses on developing innovative implantable microdevices that can deliver small doses of various cancer treatments directly to tumors in patients with head and neck cancer. By measuring how the tumor responds to each treatment, the research aims to identify the most effective therapies tailored to individual patients. This personalized approach could significantly improve treatment outcomes and reduce side effects by ensuring that patients receive the most suitable therapies based on their unique tumor characteristics.
Why it matters
Potential benefit: If successful, this research could lead to more effective and personalized treatment options for patients with head and neck cancer.
How similar studies have gone: Previous research has shown promising results with similar implantable microdevice technologies in predicting treatment responses in other cancer types.
Where this research is happening
-
Brigham and Women's Hospital
Boston, United States Active
Researchers
- Principal investigator: Jonas, Oliver — Brigham and Women's Hospital
- Study coordinator: Jonas, Oliver
Related research
Other NIH-funded projects on the same topics.
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Combined Imaging and RNA Markers to Predict Head and Neck Cancer Recurrence
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-
Biomarker to guide treatment in head and neck cancer
A biomarker test using tumor samples is being developed to predict recurrence risk in oral cancers and help tailor treatment.
-
Intensive dental care during cancer follow-up to protect teeth after head and neck radiation
A program delivered in oncology clinics to provide fluoride varnish and dental follow-up aims to reduce tooth decay and improve oral health and quality of life for head and neck cancer patients after radiation therapy.
-
AI-powered radiotherapy planning for cervical and head-and-neck cancer
A computer program helps plan radiation therapy for cervical and head-and-neck cancer patients to make treatments faster and more accurate.
-
AI-powered radiotherapy planning for cervical and head-and-neck cancer
A United Kingdom study is testing AI software that helps plan radiotherapy for cervical and head-and-neck cancer patients to save time and reduce the workload for clinicians in low-resource settings.
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AI-powered radiotherapy planning for cervical and head-and-neck cancer
A UK research team is testing an AI-based software to automatically outline cancer areas and plan radiation beams to speed up treatment for cervical and head-and-neck cancers in LMICs.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.