Creating advanced tools for analyzing proteins in biological samples
Development of Next Generation Mass Spectrometric Instrumentation for Proteomics
['FUNDING_R01'] · ROCKEFELLER UNIVERSITY · NIH-10707071
This study is working on new technology that can quickly and accurately analyze many proteins at once, which could help doctors better understand diseases and improve diagnoses for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | ROCKEFELLER UNIVERSITY (nih funded) |
| Locations | 1 site (NEW YORK, UNITED STATES) |
| Trial ID | NIH-10707071 on ClinicalTrials.gov |
What this research studies
This research focuses on developing next-generation mass spectrometric instrumentation that allows for the parallel analysis of proteins, significantly improving the speed and sensitivity of proteomic studies. By moving away from traditional sequential methods, which analyze one protein at a time, this innovative approach aims to capture a broader range of proteins in complex biological samples. Patients may benefit from enhanced diagnostic capabilities and a deeper understanding of diseases through improved proteomic analysis. The research will involve advanced technology development and testing to ensure the new instrumentation can effectively filter out noise and unwanted signals.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research include individuals with complex diseases where protein analysis is crucial for understanding their condition.
Not a fit: Patients with conditions that do not require detailed proteomic analysis may not receive direct benefits from this research.
Why it matters
Potential benefit: If successful, this research could lead to more accurate and comprehensive protein analyses, improving disease diagnosis and treatment options for patients.
How similar studies have performed: Other research has shown promise in improving mass spectrometry techniques, but this approach of massively parallel analysis is relatively novel and untested.
Where this research is happening
NEW YORK, UNITED STATES
- ROCKEFELLER UNIVERSITY — NEW YORK, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: CHAIT, BRIAN T — ROCKEFELLER UNIVERSITY
- Study coordinator: CHAIT, BRIAN T
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Communicable Diseases, Infectious Disease Pathway, Infectious Diseases, Infectious Disorder