Creating advanced sensors to detect proteins linked to diseases.
Official title: Development of Modular Synthetic Sensors for Protein Biomarker Detection
Funded at Syracuse University · NIH-11034048 · Data updated 2026-11-12
This study is working on creating new sensors that can quickly and accurately find specific proteins linked to diseases like cancer, helping patients get better and faster diagnoses by detecting important changes in their samples.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Syracuse University NIH-funded |
| Lab location | 1 site (Syracuse, United States) |
| Project start | March 1, 2023 |
| Project end | February 28, 2027 |
| Funding year | 2025 |
| Award (this year) | $272,725 |
| NIH project number | 5R01EB033412-03 |
| Project ID | NIH-11034048 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals with conditions that involve specific protein biomarkers, such as various types of cancer.
✕Less likely to help
Patients who do not have conditions associated with detectable protein biomarkers may not benefit from this research.
What this research studies
This research focuses on developing innovative synthetic sensors that can accurately detect and profile protein biomarkers associated with various diseases, particularly cancers. By engineering a unique protein nanostructure that includes a membrane protein pore and a programmable binder, the project aims to enhance the sensitivity and specificity of protein detection in complex biological samples. The sensors will be capable of identifying multiple proteins simultaneously, which is crucial for understanding disease progression and improving diagnostics. Patients may benefit from more accurate and timely detection of disease-related protein changes in their biological samples.
Why it matters
Potential benefit: If successful, this research could lead to more precise diagnostic tools for early detection of diseases, improving patient outcomes.
How similar studies have gone: Previous research has shown promising results in developing similar biosensors for protein detection, indicating a strong potential for success in this novel approach.
Where this research is happening
-
Syracuse University
Syracuse, United States Active
Researchers
- Principal investigator: Movileanu, Liviu — Syracuse University
- Study coordinator: Movileanu, Liviu
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.