Creating advanced genetic tools to improve tendon and musculoskeletal healing
Official title: Generation of intersectional genetic tools for advancing tendon and musculoskeletal research
Funded at Massachusetts General Hospital · NIH-11037272 · Data updated 2026-11-12
This study is looking at how tendon and ligament injuries heal so that we can find better ways to help people recover, using special techniques in mice to learn more about the cells involved in healing.
Quick facts
| Grant type | R21 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Massachusetts General Hospital NIH-funded |
| Lab location | 1 site (Boston, United States) |
| Project start | September 18, 2024 |
| Project end | August 31, 2026 |
| Funding year | 2024 |
| Award (this year) | $359,133 |
| NIH project number | 1R21AR085241-01 |
| Project ID | NIH-11037272 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are individuals suffering from tendon or ligament injuries, including both young active individuals and older adults.
✕Less likely to help
Patients with non-tendon related musculoskeletal issues or those who do not have tendon injuries may not benefit from this research.
What this research studies
This research focuses on understanding how tendon and ligament injuries heal, which is crucial for improving treatment options. By studying specific cell types and pathways involved in tendon formation and repair, the researchers aim to develop new genetic tools that can target these cells more effectively. This approach uses advanced genetic techniques in mice to identify and manipulate tendon cells, which could lead to better healing strategies for patients with tendon injuries. The goal is to enhance our understanding of tendon biology and improve recovery outcomes for individuals suffering from these injuries.
Why it matters
Potential benefit: If successful, this research could lead to improved treatments for tendon injuries, enhancing healing and reducing pain for patients.
How similar studies have gone: Previous research using genetic tools in related fields has shown promise, indicating that this approach could yield valuable insights and advancements in tendon healing.
Where this research is happening
-
Massachusetts General Hospital
Boston, United States Active
Researchers
- Principal investigator: Galloway, Jenna L — Massachusetts General Hospital
- Study coordinator: Galloway, Jenna L
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.