Creating advanced 3D models for testing cancer treatments
VivoSpheres: Tissue-Engineered Spheroidal Models for High-Throughput Screening
This study is working on creating new 3D models that better mimic tumors to help researchers find effective cancer treatments faster and more reliably.
Quick facts
| Grant type | Sbir 1 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Vivosphere LLC NIH-funded |
| Lab location | 1 site (Auburn, United States) |
| Project ID | NIH-10921674 on NIH RePORTER |
What this research studies
This research focuses on developing innovative three-dimensional (3D) spheroidal models that enhance the drug discovery process for cancer treatments. By utilizing a microfluidic platform, the study aims to produce consistent and high-quality cell-laden hydrogel microspheres, known as VivoSpheres, which can better mimic the tumor environment compared to traditional two-dimensional models. These models will allow researchers to test various cancer drugs more effectively, potentially leading to faster and more reliable results in identifying effective treatments.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with various types of cancer who may benefit from new treatment options.
Not a fit: Patients with non-cancerous conditions or those not seeking new cancer treatments may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective cancer therapies being developed more quickly and efficiently.
How similar studies have performed: Previous research has shown that 3D models can significantly improve drug testing outcomes, indicating a promising direction for this novel approach.
Where this research is happening
Auburn, United States
- Vivosphere LLC — Auburn, United States (Active)
Researchers
- Principal investigator: Tian, Yuan — Vivosphere LLC
- Study coordinator: Tian, Yuan
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.