Creating accurate animal models to better understand and treat diseases
Disease Modeling Unit
This study is creating special mouse models that closely resemble human diseases to help researchers test new treatments, making it easier to turn genetic discoveries into real therapies for patients like you.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Jackson Laboratory NIH-funded |
| Lab location | 1 site (Bar Harbor, United States) |
| Project ID | NIH-10904728 on NIH RePORTER |
What this research studies
This research focuses on developing genetically precise mouse models that mimic human diseases, which are essential for testing new treatments. By utilizing advanced techniques like high-throughput sequencing and CRISPR technology, the project aims to enhance the predictive capabilities of these models. This will allow researchers to conduct detailed studies and preclinical testing, ultimately facilitating the translation of genetic discoveries into effective therapies for patients. The Jackson Laboratory, with its extensive expertise, is committed to refining and expanding its infrastructure to support this critical work.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with genetic diseases that can be modeled in mice, as well as those interested in participating in clinical trials stemming from these findings.
Not a fit: Patients with conditions that cannot be modeled in animal systems or those not eligible for clinical trials may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to more effective treatments for various diseases by improving the accuracy of preclinical testing.
How similar studies have performed: Previous research has shown success in developing animal models for human diseases, indicating that this approach has the potential for significant advancements.
Where this research is happening
Bar Harbor, United States
- Jackson Laboratory — Bar Harbor, United States (Active)
Researchers
- Principal investigator: Murray, Stephen a — Jackson Laboratory
- Study coordinator: Murray, Stephen a
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.