Creating a web tool to predict how well nanoparticles deliver drugs to tumors
Development of a web-based predictive model of nanoparticle delivery to tumors by integrating physiologically-based pharmacokinetic modeling with artificial intelligence
['FUNDING_R01'] · UNIVERSITY OF FLORIDA · NIH-10887409
This study is working on a smart online tool that helps doctors figure out the best way to deliver tiny cancer-fighting particles to tumors, which could make cancer treatments more effective for patients.
Quick facts
| Phase | ['FUNDING_R01'] |
|---|---|
| Study type | Nih_funding |
| Sex | All |
| Sponsor | UNIVERSITY OF FLORIDA (nih funded) |
| Locations | 1 site (GAINESVILLE, UNITED STATES) |
| Trial ID | NIH-10887409 on ClinicalTrials.gov |
What this research studies
This research aims to develop a web-based predictive model that enhances the delivery of nanoparticle-based drugs to tumors. By integrating advanced pharmacokinetic modeling with artificial intelligence, the project seeks to improve the understanding of how these nanoparticles behave in the body, particularly in tumor-bearing mice. The approach involves training the model using extensive datasets to accurately predict how different nanoparticles distribute in tissues and reach tumors. This could lead to more effective cancer treatments by optimizing drug delivery methods.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals with cancer who may benefit from advanced nanoparticle-based therapies.
Not a fit: Patients who are not undergoing treatment involving nanoparticle-based therapies may not receive any benefit from this research.
Why it matters
Potential benefit: If successful, this research could significantly improve the effectiveness of cancer treatments using nanoparticle drug delivery systems.
How similar studies have performed: Other research has shown promise in using similar computational modeling approaches to enhance drug delivery, indicating potential for success in this novel application.
Where this research is happening
GAINESVILLE, UNITED STATES
- UNIVERSITY OF FLORIDA — GAINESVILLE, UNITED STATES (ACTIVE)
Researchers
- Principal investigator: LIN, ZHOUMENG — UNIVERSITY OF FLORIDA
- Study coordinator: LIN, ZHOUMENG
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions: Anti-Cancer Agents