Creating a wearable device to help surgeons identify brain tumors during surgery
Official title: Development of a Wearable Fluorescence Imaging Device for IntraoperativeIdentification of Brain Tumors
Funded at Biopticstechnology, LLC · NIH-10697009 · Data updated 2026-11-12
This study is testing a new, affordable device called FLoupe™ that helps surgeons see brain tumors more clearly during surgery, making it easier to remove cancerous tissue and improve patient outcomes.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Biopticstechnology, LLC NIH-funded |
| Lab location | 1 site (Lexington, United States) |
| Project start | September 25, 2023 |
| Project end | August 31, 2026 |
| Funding year | 2023 |
| Award (this year) | $1,027,934 |
| NIH project number | 2R42CA243600-02 |
| Project ID | NIH-10697009 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients diagnosed with malignant gliomas who are scheduled for surgical resection.
✕Less likely to help
Patients with non-malignant brain tumors or those not undergoing surgery may not benefit from this research.
What this research studies
This research focuses on developing a low-cost wearable fluorescence imaging device, known as FLoupe™, that can be used during brain surgeries to enhance the identification of malignant gliomas. By integrating this device with traditional surgical eye loupes, surgeons can visualize cancerous tissues in real-time, potentially improving surgical outcomes. The device aims to overcome the limitations of existing imaging systems, which are often expensive and cumbersome. Initial tests have shown promising results in identifying tumors during surgeries.
Why it matters
Potential benefit: If successful, this research could significantly improve the accuracy of brain tumor surgeries, leading to better patient outcomes and higher survival rates.
How similar studies have gone: Previous research has shown that fluorescence imaging can enhance tumor detection during surgeries, indicating a promising avenue for this novel approach.
Where this research is happening
-
Biopticstechnology, LLC
Lexington, United States Active
Researchers
- Principal investigator: Yu, Guoqiang — Biopticstechnology, LLC
- Study coordinator: Yu, Guoqiang
Related research
Other NIH-funded projects on the same topics.
-
ONC206 for children with brain tumors: a first-in-children trial
A first-in-children trial will test the safety and early signs of effectiveness of ONC206, taken by mouth, in kids with malignant brain tumors like diffuse midline gliomas.
-
ONC206 for children with malignant brain tumors
A first-in-children trial tests the safety and early effectiveness of a pill that can cross the brain barrier to treat pediatric brain tumors.
-
ONC206 for children with dangerous brain tumors
A first-in-children study tests the safety and early effectiveness of an oral drug, ONC206, for kids with high-risk brain tumors that have spread or recurred.
-
Oral bacteria and brain metastasis: how the mouth may influence brain tumors
A study exploring how oral microbes may affect brain metastases and patient outcomes, with potential to guide new microbiome-based approaches.
-
Bioengineered brain barrier chip to improve drug screening for brain tumors
A small, patient-friendly brain barrier chip is being developed to test drugs for glioblastoma more accurately before they reach clinical trials.
-
Understanding how epigenetic changes drive pediatric brain tumor recurrence and how reversing them could help
A pediatric brain cancer research project is exploring how an epigenetic change (H3K27M) and tumor environment contribute to tumor coming back, using a reversible mouse model to study potential ways to prevent recurrence.
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.