Creating a virtual vocal tract to help people speak using brain signals

A virtual vocal tract for speech output using non-invasive brain-computer interface

NIH-funded research University of Kansas Lawrence · NIH-10433983

This study is testing a new way for people with severe speech difficulties, like those with ALS, to communicate better by using a brain-computer interface that turns their thoughts into speech, helping them express themselves more easily.

Quick facts

Grant typeR01 grant
Study typeNIH-funded research
Funding institutionUniversity of Kansas Lawrence NIH-funded
Lab location1 site (Lawrence, United States)
Project IDNIH-10433983 on NIH RePORTER

What this research studies

This research explores the use of brain-computer interfaces (BCIs) to help individuals with severe speech impairments, such as those caused by amyotrophic lateral sclerosis (ALS), communicate more effectively. By developing a virtual vocal tract that can produce both vowels and consonants, the project aims to enable users to form words and sentences, enhancing their ability to express themselves. The approach builds on previous studies and technologies, focusing on translating brain signals into speech output without the need for physical movement. Participants will engage in practice sessions to learn how to use this innovative communication tool.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults with severe speech impairments, particularly those diagnosed with ALS or similar conditions.

Not a fit: Patients who have intact speech capabilities or those with conditions that do not affect communication may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could provide a new means of communication for individuals who have lost their ability to speak due to neurological conditions.

How similar studies have performed: Previous studies have shown promise in using BCIs for speech production, but this approach aims to expand on those findings by enabling more complex speech output.

Where this research is happening

Lawrence, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Conditions Amyotrophic Lateral Sclerosis Motor Neuron DiseaseGehrig's DiseaseLou Gehrig Disease
Last reviewed 2026-06-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.