Creating a virtual platform to simulate drug equivalence for better treatment options
Official title: A State-of-the-Art Virtual Bioequivalence Platform and Case Studies on Complex Formulations, Systemic and Local Concentration-based Bioequivalence
Funded at Certara UK Limited · NIH-10913489 · Data updated 2026-11-12
This study is working on a new computer program that can mimic how different versions of medications work in the body, which could help make drug testing safer and cheaper for patients by reducing the need for traditional clinical trials.
Quick facts
| Grant type | U01 cooperative agreement |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Certara UK Limited NIH-funded |
| Lab location | 1 site (Sheffield, United Kingdom) |
| Project start | July 3, 2023 |
| Project end | July 2, 2026 |
| Funding year | 2024 |
| Award (this year) | $249,837 |
| NIH project number | 5U01FD007904-02 |
| Project ID | NIH-10913489 on NIH RePORTER |
Who could benefit from this research
✓Could help
Ideal candidates for this research are patients who are involved in or affected by the development of new drug formulations.
✕Less likely to help
Patients who are not participating in drug development or who are not affected by the specific formulations being tested may not benefit from this research.
What this research studies
This research focuses on developing a virtual bioequivalence (VBE) platform that uses advanced computer modeling to simulate how different drug formulations behave in the body. By creating realistic virtual patient cohorts, the platform aims to replace traditional clinical trials, which can be costly and expose patients to unnecessary treatments. The project will establish clear workflows and case studies to ensure that this innovative approach is widely adopted by the pharmaceutical industry and regulatory bodies, ultimately improving drug development processes.
Why it matters
Potential benefit: If successful, this research could significantly speed up drug development and provide safer, more effective treatment options for patients.
How similar studies have gone: Other research has shown promise in using virtual simulations for drug development, indicating that this approach could lead to significant advancements in the field.
Where this research is happening
-
Certara UK Limited
Sheffield, United Kingdom Active
Researchers
- Principal investigator: Bois, Frederic — Certara UK Limited
- Study coordinator: Bois, Frederic
Related research
Other NIH-funded projects on the same topics.
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About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page.