Creating a vaccine for Chlamydia trachomatis using pigs
Development of a Chlamydia trachomatis Vaccine in an Outbred Pre-exposed Swine Animal Model
This study is testing a new vaccine for Chlamydia, a common infection that can cause serious health problems, using pigs to see how well it can help the immune system fight off the infection, so we can better protect people in the future.
Quick facts
| Grant type | R01 grant |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Veterinarmedizinische Universitat Wien NIH-funded |
| Lab location | 1 site (Wien, Austria) |
| Project ID | NIH-10983729 on NIH RePORTER |
What this research studies
This research focuses on developing a vaccine for Chlamydia trachomatis, a common bacterial sexually transmitted infection that can lead to serious health issues like infertility. The study uses pigs, which are closely related to humans in terms of immune response, to test new vaccine formulations and understand how the immune system can be primed to fight this infection. By using pigs that have been previously exposed to a related chlamydia species, researchers aim to simulate human responses to vaccination. The research is structured in phases to systematically evaluate the vaccine's effectiveness and immune response.
Who could benefit from this research
Good fit: Ideal candidates for benefiting from this research are individuals at risk of Chlamydia trachomatis infections, particularly sexually active individuals.
Not a fit: Patients who are already infected with Chlamydia trachomatis and are seeking immediate treatment may not benefit directly from this research.
Why it matters
Potential benefit: If successful, this research could lead to an effective vaccine that prevents Chlamydia trachomatis infections, significantly reducing related health complications in humans.
How similar studies have performed: While there have been successful vaccine developments for other bacterial infections, this specific approach using pigs for Chlamydia trachomatis is relatively novel and untested in this context.
Where this research is happening
Wien, Austria
- Veterinarmedizinische Universitat Wien — Wien, Austria (Active)
Researchers
- Principal investigator: Kaeser, Tobias E — Veterinarmedizinische Universitat Wien
- Study coordinator: Kaeser, Tobias E
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.