Creating a urine test to detect non-muscle-invasive bladder cancer

Development of a Urine Genetic Test for NonMuscle Invasive Bladder Cancer

['FUNDING_SBIR_1'] · JBS SCIENCE, INC. · NIH-10759106

This study is working on a new urine test that looks at genetic information to help people with non-muscle-invasive bladder cancer get better treatment and monitor their condition more effectively.

Quick facts

Phase['FUNDING_SBIR_1']
Study typeNih_funding
SexAll
SponsorJBS SCIENCE, INC. (nih funded)
Locations1 site (DOYLESTOWN, UNITED STATES)
Trial IDNIH-10759106 on ClinicalTrials.gov

What this research studies

This research focuses on developing a urine genetic test specifically for non-muscle-invasive bladder cancer (NMIBC), which is a common type of bladder cancer. The test aims to provide comprehensive genetic information that can help guide treatment decisions and monitor for recurrence. By analyzing tumor cells and cell-free DNA in urine, the researchers hope to improve the accuracy of diagnosis and treatment stratification for patients with NMIBC. This innovative approach addresses the current limitations in distinguishing between NMIBC and muscle-invasive bladder cancer.

Who could benefit from this research

Good fit: Ideal candidates for this research are individuals diagnosed with non-muscle-invasive bladder cancer who require ongoing monitoring and treatment guidance.

Not a fit: Patients with muscle-invasive bladder cancer or those without a diagnosis of bladder cancer may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could lead to a more accurate and less invasive method for diagnosing and monitoring bladder cancer, ultimately improving patient outcomes.

How similar studies have performed: Previous research has shown promise in using genetic testing for cancer diagnosis, indicating that this approach may lead to significant advancements in bladder cancer management.

Where this research is happening

DOYLESTOWN, UNITED STATES

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.

View on NIH RePORTER →

Conditions: Bladder Cancer, Urinary Bladder Cancer

Last reviewed 2026-05-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.