NIH-funded research Sbir 2 grant

Creating a tool to map brain spaces for diagnosing Alzheimer's disease

Official title: Development of perivascular space mapping toolset as a diagnostic aid for Alzheimer's disease

Funded at Neuroscope INC. · NIH-10921984 · Data updated 2026-11-12

This study is working on a new, easy way to use MRI scans to look at important areas in the brain that help clear out waste, which could help doctors better diagnose and track Alzheimer's disease, especially for those receiving treatment.

More s Disease research and trials

Quick facts

Grant typeSbir 2 grant
Study typeNIH-funded research
Funding institutionNeuroscope INC.
NIH-funded
Lab location1 site (Scarsdale, UNITED STATES)
Project startAugust 1, 2024
Project endJuly 31, 2026
Funding year2024
Award (this year)$1,193,370
NIH project number1R44AG087855-01
Project IDNIH-10921984 on NIH RePORTER

Who could benefit from this research

Could help

Ideal candidates for this research include individuals diagnosed with Alzheimer's disease or related dementias, particularly those undergoing treatment with amyloid-clearing therapies.

Less likely to help

Patients with other forms of dementia unrelated to Alzheimer's disease may not benefit from this research.

What this research studies

This research focuses on developing a non-invasive tool that maps the perivascular spaces in the brain using MRI technology. These spaces play a crucial role in clearing metabolic waste, and their integrity is linked to Alzheimer's disease and related dementias. By assessing these spaces, the tool aims to improve the diagnosis and monitoring of Alzheimer's disease, especially in patients undergoing amyloid-clearing treatments. The approach combines advanced imaging techniques with clinical criteria to enhance understanding and management of the disease.

Why it matters

Potential benefit: If successful, this research could lead to improved diagnostic accuracy and monitoring for patients with Alzheimer's disease.

How similar studies have gone: Previous research has shown promising results in using MRI for brain mapping in Alzheimer's patients, indicating that this approach has potential for success.

Where this research is happening

  • Neuroscope INC.
    Scarsdale, United States
    Active

Researchers

  • Principal investigator: Choupan, Jeiran — Neuroscope INC.
  • Study coordinator: Choupan, Jeiran

Related research

Other NIH-funded projects on the same topics.

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page.
Last reviewed 2026-11-15 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.