Creating a tool to help patients with acute myeloid leukemia make treatment decisions

Developing a Values Elicitation Tool to Improve Treatment Decision-Making in Acute Myeloid Leukemia

NIH-funded research Univ of North Carolina Chapel Hill · NIH-11112298

This study is creating a helpful tool called PRIME for people with acute myeloid leukemia (AML) to express what matters most to them in their treatment, so they can make better decisions with their doctors about their care.

Quick facts

Grant typeCareer grant
Study typeNIH-funded research
Funding institutionUniv of North Carolina Chapel Hill NIH-funded
Lab location1 site (Chapel Hill, United States)
Project IDNIH-11112298 on NIH RePORTER

What this research studies

This research focuses on developing a tool called PRIME that helps patients with acute myeloid leukemia (AML) clarify their treatment preferences based on their personal values. By using a method called best-worst scaling, the tool generates a personalized report that assists patients and clinicians in shared decision-making. The goal is to improve the treatment decision-making process, especially as new therapies for AML become available. Patients will be engaged in discussions about what matters most to them, whether it's quality of life or survival.

Who could benefit from this research

Good fit: Ideal candidates for this research are adults diagnosed with acute myeloid leukemia who are facing treatment decisions.

Not a fit: Patients who are not diagnosed with acute myeloid leukemia or those who are not actively involved in treatment decision-making may not benefit from this research.

Why it matters

Potential benefit: If successful, this research could empower patients with AML to make more informed treatment choices that align with their personal values.

How similar studies have performed: Previous research has shown promise in using values elicitation tools for patient decision-making, indicating that this approach could be effective.

Where this research is happening

Chapel Hill, United States

Researchers

About this research

  1. This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
  2. Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
  3. For full project details, budget, and progress reports, visit the official NIH RePORTER page below.
Last reviewed 2026-06-13 by the Find a Trial editorial team. Information on this page is for educational purposes and is not medical advice. Always consult qualified healthcare professionals about clinical trial participation.