Creating a tool to detect cancer in Barrett's esophagus using a portable device
Development and Validation of an Automated Algorithm for Real-time Detection of Neoplasia in Barrett's Esophagus using a Low-cost, Portable Microendoscope
This study is testing a new, easy-to-use imaging tool that helps doctors spot early signs of cancer in patients with Barrett's esophagus, making it simpler for them to monitor your health without needing extra training.
Quick facts
| Grant type | NIH-funded research |
|---|---|
| Study type | NIH-funded research |
| Funding institution | Baylor College of Medicine NIH-funded |
| Lab location | 1 site (Houston, United States) |
| Project ID | NIH-11063106 on NIH RePORTER |
What this research studies
This research focuses on improving the detection of neoplasia, which can lead to esophageal cancer, in patients with Barrett's esophagus. It utilizes a low-cost, portable imaging technology called confocal high-resolution microendoscopy (cHRME) that provides detailed images of the esophagus. The project aims to develop an automated algorithm that can analyze these images in real-time, making it easier for healthcare providers to identify potential cancerous changes without needing specialized training. By integrating traditional clinical risk factors, the algorithm will enhance risk assessment for patients undergoing surveillance.
Who could benefit from this research
Good fit: Ideal candidates for this research are individuals diagnosed with Barrett's esophagus who are undergoing routine surveillance for neoplasia.
Not a fit: Patients without Barrett's esophagus or those who are not undergoing surveillance for esophageal neoplasia may not benefit from this research.
Why it matters
Potential benefit: If successful, this research could lead to earlier and more accurate detection of esophageal cancer, improving patient outcomes.
How similar studies have performed: Previous research has shown promising results with similar automated detection approaches in other areas of cancer diagnosis, indicating potential success for this novel application.
Where this research is happening
Houston, United States
- Baylor College of Medicine — Houston, United States (Active)
Researchers
- Principal investigator: Tan, Mimi Chang — Baylor College of Medicine
- Study coordinator: Tan, Mimi Chang
About this research
- This is an active NIH-funded research project — typically early-stage science, not a clinical trial accepting patient enrollment.
- Some NIH-funded labs run parallel clinical studies or seek volunteers for related work. To check, contact the principal investigator or institution listed above.
- For full project details, budget, and progress reports, visit the official NIH RePORTER page below.